| Development and Commercialization of Real Time Compensation of Field Changes in MR Imaging |
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Institute : National Institute of Neurological Disorders and Stroke (NINDS)
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| Description of Technology/Invention :
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The National Institute of Neurological Disorders and Stroke (NINDS) of the National Institutes of Health (NIH) seeks a Cooperative Research and Development Agreement (CRADA) Collaborator to work with NINDS in the development of a method of providing real time compensation of respiration induced field changes in Magnetic Resonance (MR)imaging leading to the incorporation of the method in commercially available products.
Summary of the Technology
During an MRI scan of the brain, real time compensation of respiration induced field changes is accomplished by modulating the frequency of applied RF energy, and the intensity of applied spatially varying magnetic fields as a function of respiration state. Prior to scanning, changes to the local magnetic field in the head of the subject are measured as a function of respiration. Changes as a function of gradient and shim currents are also determined. The changes as a function of respiration are combined with the changes as a function of gradient/shim currents to produce each current as a function of respiration. This result is utilized in real time to compensate for fluctuations in the spatially varying magnetic field due to respiration.
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| Potential Areas of Application : |
● MR imaging of humans, including imaging of brain or chest
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| Main Advantages of Technology/Invention
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| ● Reduces MR imaging artifacts including ghosting, blurring and subtle image shifts |
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| Current State of Development : |
| ● Tested on humans, testing in additional populations needed. |
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| Patent Status : |
| U.S. Provisional Application No. 60/781,246 4 filed March 10, 2006 |
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| NIH Reference Number: |
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| Contact Information : |
| Martha T. Lubet Ph.D., NIH Technology Transfer Office |
| Phone: 301 435-3120 |
Email: lubetm@mail.nih.gov
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| Last Updated: 7/25/2006 |
